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Grey's Anatomy Season 22

Grey's Anatomy

Season 22

October 9, 2025 18 episodes

The twenty-second season will focus on intense, large-scale disasters, including a major bridge collapse bringing in dozens of critically injured patients at Grey Sloan Memorial, alongside high-stakes personnel changes. Dr. Meredith Grey and Dr. Nick Marsh decide to marry after Nick is severely injured in the bridge collapse, with Meredith realizing she doesn't want to let fear dictate her life. The season features the departure of long-time series regulars Dr. Owen Hunt and Dr. Teddy Altman, who leave for a new life in France after surviving a near-fatal plunge in his car during the bridge collapse, marking an end to their long-running storyline.

All Episodes

Only the Strong Survive
E1
Guide

E1. Only the Strong Survive

43m Oct 9, 2025

After the catastrophic hospital explosion, Grey Sloan's staff scrambles to save not only their patients' lives but also their own. Confronted with impossible surgical decisions and emotional turmoil, they fight to preserve life amid devastation.

We Built This City
E2
Guide

E2. We Built This City

44m Oct 16, 2025

The team at Grey Sloan navigates a chaotic first day of surgical rotations amid hospital renovations. Meanwhile, Meredith spends time with Amelia.

Between Two Lungs
E3
Guide

E3. Between Two Lungs

43m Oct 23, 2025

A high-risk lung transplant pushes the surgical team to their limits. Meanwhile, Bailey juggles a trauma patient whose treatment hangs in the balance.

Goodbye Horses
E4
Guide

E4. Goodbye Horses

43m Oct 30, 2025

The interns juggle a bizarre trauma, while a complex breast reconstruction forces Meredith into a tense partnership.

Sometimes I Feel Like a Motherless Child
E5
Guide

E5. Sometimes I Feel Like a Motherless Child

44m Nov 6, 2025

Jo navigates a challenging case with a pregnant mother, while Blue and Jules care for a diabetic patient. Meanwhile, Simone treats a patient with a surprising revelation.

When I Crash
E6
Guide

E6. When I Crash

44m Nov 13, 2025

Grey Sloan takes in patients following a catastrophic bus accident. Teddy and Owen have an awkward encounter, and Richard tests Bailey's patience.

Skyfall
E7
Guide

E7. Skyfall

44m Jan 8, 2026

Winston and Ben fight to save Jo's life, while Teddy supports Link. Owen and Jules battle to save a young man, and Lucas forms an unexpected bond with a patient.

Heavy on Me
E8
Guide

E8. Heavy on Me

44m Jan 15, 2026

Bailey and Owen join forces to save a tumor patient, while Richard faces an internal battle. Meanwhile, Jules struggles with her feelings for Winston.

Fortunate Son
E9
Guide

E9. Fortunate Son

43m Jan 22, 2026

Richard continues to navigate his health. Meanwhile, Meredith and Nick are visited by Nick's estranged sister from Boston.

Strip That Down
E10
Guide

E10. Strip That Down

44m Jan 29, 2026

Addison Montgomery returns to Grey Sloan, seeking assistance with a patient with a neurological condition. Bailey joins Owen and Blue on a paramedic ride-along.

(If You Want It) Do It Yourself
E11
Guide

E11. (If You Want It) Do It Yourself

45m Feb 26, 2026

Teddy and Winston clash over a case, while Owen and Jules treat a urologist. Lucas struggles with prioritizing patients.

Get Lucky
E12
Guide

E12. Get Lucky

44m Mar 5, 2026

Tensions rise as Teddy and Winston take on a complex procedure, while Kavita and Ben try and impress the new plastics attending. Jo and Link leave the babies with a nanny for the first time.

Love the Way You Lie
E13
Guide

E13. Love the Way You Lie

44m Mar 12, 2026

Richard tackles a shocking case on his first day back, while Kavita and Jules prepare for a high-stakes presentation. Bailey must have a difficult conversation with a beloved patient, and Jo works to baby-proof the loft.

Wrecking Ball
E14
Guide

E14. Wrecking Ball

43m Mar 19, 2026

A couple lands in the hospital with life-altering injuries after a wrecking ball destroys their home. Lucas and Simone struggle to support a young, terminally ill patient, and Richard hosts a prostate screening event.

Take Me to the River
E15
Guide

E15. Take Me to the River

43m Mar 26, 2026

Bailey and Blue are forced to confront the emotional costs of experimental care. Meanwhile, Owen, Teddy, Simone and Dani help out at a busy rural hospital, and Richard attempts to spread information about early prostate screenings to the community.

Feel It Still
E16
Guide

E16. Feel It Still

44m Apr 2, 2026

Jo returns for her first full day back from leave, and Owen struggles to keep it together when someone close to him is admitted to Grey Sloan. Meanwhile, Bailey navigates hospital leadership.

Through the Fire
E17
Guide

E17. Through the Fire

43m Apr 30, 2026

A Station 19 firefighter lands in the ER for severe burn treatment, and the team treats an elderly patient impaled by an art structure. A Fox Foundation innovation competition reunites Meredith and Bailey.

Bridge Over Troubled Water
E18
Guide

E18. Bridge Over Troubled Water

43m May 7, 2026

After a catastrophic bridge collapse sends dozens of victims to Grey Sloan, the hospital activates its full disaster response as they race to treat a surge of critically injured patients, including one of their own.

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